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| 书名： | Biochemical Protozoology As A Basis For Drug Design | |
|---|---|---|
| 作者： | Coombs, Graham H. | |
| 出版时间： | 1991-10-07 | |
| ISBN： | 9780748400010(P-ISBN) ，9780203221259(O-ISBN) | |
| 摘要： | ||
| 摘要： | ||
书目详情：
Book CoverTitleContentsPrefaceContributorsThe current status of biochemical protozoologyThe biochemistry of malaria: an overviewPneumocystis carinii: potential targets for chemotherapeutic attackGiardia cysts: their biochemistry and metabolismThe biochemical activities and importance of the ciliate protozoa in the rumen ecosystemEnergy metabolism of anaerobic parasitic protistsThe effects of environmental factors on the metabolism of Giardia and TrichomonasEnergy metabolism in Giardia intestinalisAmino acids catabolism in anaerobic protistsIntermediary metabolism of LeishmaniaGlycosomesMitochondrial metabolism of African trypanosomesMitochondria of PlasmodiumProteinases of mammals: an overviewProteinases of parasitic protozoa: an overviewNew approaches to molecular analysis of proteinases of parasitic protozoaProteinases of Trypanosoma cruziProteinases of African trypanosomesCysteine proteinases of leishmaniasThe promastigote surface proteinase of LeishmaniaProteinases of trichomonads and GiardiaThe cysteine proteinase of Entamoeba histolytica: cloning of the gene and its role as a virulence factorAmoebapain, the major proteinase of pathogenic Entamoeba histolyticaProteinases of malaria parasitesPlasmodium proteinases during the erythrocytic phase of infectionProteinases of BabesiaGlycosylated phosphatidylinositols of the trypanosomatidaeStructural variations of the leishmanial lipophosphoglycanLipid biochemistry of trypanosomatidsLipids and lipid metabolism of trichomonads Tritrichomonas foetus and Trichomonas vaginalis)Lipid composition of the membranes of malaria-infected erythrocytes and the role of drug-lipid interactions in the mechanism of action of chloroquine and other antimalarialsAdaptation of Leishmania species to an acidic environmentGlucose uptake mechanisms as potential targets for drugs against trypanosomatidsTransport and compartmentation in Entamoeba histolyticaSubstrate specificities for malaria-inducible red cell transport in relation to parasite metabolismNucleoside transport in malaria- and Babesia-infected cellsApproaches to investigating cation metabolism in malaria-infected erythrocytesCation-transporting ATPases of PlasmodiumIs the multidrug resistant protein of the malaria parasite involved in drug resistance?S-Adenosylmethionine metabolism in parasitic protozoaMethionine recycling as a target for antiprotozoal drug developmentPolyamine metabolism in anaerobic protozoaPolyamine metabolism in African trypanosomesTrypanothione metabolism as a target for drug design: molecular modelling of trypanothione reductaseThe antioxidant enzymes glutathione reductase and trypanothione reductase as drug targetsPolyamine biosynthesis as a target for the chemotherapy of trypanosomatid infectionsNew approaches to the chemotherapy of drug-resistant malariaPurine metabolism in parasitic protozoa and its relationship to chemotherapyPhosphomonoesterases of parasitic protozoaGenetic analysis of folate transport and metabolism in Leishmania donovaniFolate metabolism as a target for chemotherapy of malariaProtein synthesis as a target for antiprotozoal drugsThe mode of action of benzimidazoles against Giardia and their chemotherapeutic potential against Giardia and other parasitic protozoaBiochemical and molecular mechanisms of resistance to nitroheterocyclic drugs in Giardia intestinalisPossibilities for new antiprotozoal drugs: the TDR/WHO approach
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